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They have good power and a high rate of fire, allowing you to mow down medium and close range enemies.
Automatic Weapons: Submachine guns, M16s, and their ilk are your bread and butter. But they are great in a group and can clean up long-range, incoming enemies while the rest of the team waits patiently for them to reach shotgun range. Rifles: Powerful and accurate at long ranges, they are almost useless in tense, swarming situations because they take a while to aim and shoot. Use them in hallways and other tight locations. They deal a lot of damage and have a wide spread of fire, but they are inaccurate at long distances. Shotguns: Coming in chrome, pump, and automatic options, shotguns are great options in close quarters. When you start out, you will only have access to a small variety of them, but more powerful weapons and items will appear as you progress. There is a variety of items and weapons available in Left 4 Dead, each with their own pros and cons. Great at creating walls against the hordes of dead, and essential against the monstrous "Tanks." Molotov Cocktails: Explode on impact, and leave a temporary lake of fire that hurts all Infected and humans that walk through it. After a few seconds, as the infected crowd the spot, the bomb explodes, killing them all. Pipe Bombs: Like bile bombs, these cause Inflected to leave you and flock to the spot where you threw it. If you throw it on another Zombie, the other Infected will attack them instead of you. Bile Bombs: A grenade that causes all regular zombies to flock to the spot where it fell, ignoring you. Use them right before huge moments, or if you need to get to a teammate to save them quickly. Most importantly, it keeps you from "flinching," which is when you are temporarily unable to shoot after being hit. Adrenaline Shots: Provides a small health boost, and boosts your running speed. This is incredibly helpful, however, for final events, where the extra boost saves a Medkit and gets you through the challenging events, allowing you to heal later fully. Pain Pills: Gives you a temporary boost of health, though it will disappear after some time. Aside from weapons, there are other items available for pick-up, most of which should be reserved for tense or serious situations. Use items effectively in tense situations. No zombies can enter it until you open the door, so this is a perfect place to catch your breath. At the end of each chapter is a safe house with supplies, medkits, and ammunition. The basic objective of the game is always "move forward." Levels are more or less linear, and your challenge is to make it to the end. As you play through each game mode, note where the major events and challenges fall, helping you stay better prepared next time you play. At the end of most chapters is a big event you must survive, and at the end of each setting is usually the most difficult challenge seen so far. Each chapter is it's own level, which is often begins with ease before getting progressively more difficult. All of them, however, are built on the same foundation: You have a setting, such as a mall, rainy town, or carnival, and there are 5 Chapters in each setting to survive. When playing L4D2, you can choose a variety of different modes. Understand the layout of a typical L4D2 level. They are good options in the early difficulties, and, with the exception of chainsaws, can be used infinitely. Melee Weapons: Katanas, baseball bats, chainsaws, crowbars, and other melee weapons attack in a wide swath in front of you, often killing Infected instantly. You should always try and have 2-3 Medkits, at a minimum, in your party. Medkits: Medkits heal your character completely. If you find another one on the ground, you can pick it up to dual wield them, effectively giving you double power, shots, and firing rate.
Pistols are weak but accurate and, most importantly, have unlimited ammunition.
On the first level, they sit on a table right next to the door. At the beginning of every level there are several Medkits, which are thick, rectangular red packs, and several weapons. Pick up the Medkit and nearby weapons in the opening location.